- delta-9-tetrahydrocannabinol (THC)
- tetrahydrocannabivarin (THCV)
- cannabigerol (CBG)
- cannabidiol (CBD)
- cannabidiolic acid (CBDA)
Each chemical acts on different receptors in different ways. For example, THCV blocks the mind-altering effects of THC while simultaneously combatting inflammation in the body, which may help relieve symptoms of Parkinson’s disease and protect against liver damage. It also changes how the serotonin receptor behaves during psychosis, potentially offering a treatment for schizophrenia.
Meanwhile, CBG’s unique profile of activity at adrenaline and serotonin receptors makes it good for treating pain. CBD and CBDA, on the other hand, are better candidates to treat nausea. Other possible uses of cannabinoids include treating stroke, PTSD, epilepsy, and drug addiction. However, there are dozens of strains of medical marijuana on the market, each claiming to have different properties for treating different symptoms. “We’ve got thousands of patients who’ve been using medical marijuana now in some kind of legal regime for dozens of years, and nobody’s ever tracked these patients over time,” he said. “We could track the patients, we could map the patients’ [symptoms] with the particular cannabis that they’re using, and we could be learning from that interaction between patient and plant to see: Are there some combinations of cannabinoids that are better for certain syndromes and symptoms than others?”